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House describes himself as “a board-certified diagnostician with a double specialty of infectious illness and nephrology”. Dr. James Wilson , House’s one true friend, is the top of the Department of Oncology. Dr. Lisa Cuddy , an endocrinologist, is House’s boss, as she is the hospital’s dean of medicine House & Home Improvement news and chief administrator. House has a complex relationship with Cuddy, and their interactions usually contain a high degree of innuendo and sexual rigidity. In the sixth episode of season five, “Joy”, they kiss for the first time.

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